An Emerging Trends on Delivering Nanofibers
DOI:
https://doi.org/10.64261/qvjr7624Keywords:
Nanofiber, Polymers, Electro spinning, Tissue engineering, Gene-deliveryAbstract
Nanofibers have a lot of surface area, porosity, and surface functionalities that can be changed. Nanofiber technology is being investigated by numerous researchers as a possible remedy for the issues that exist today in a number of different disciplines. It treats pain, wound healing, neurological diseases, gastrointestinal tract-associated diseases, infectious diseases, cardiovascular issues, and contraception. Numerous manufacturing methods, including electrospinning, phase separation, physical 3fabrications, and chemical synthesis, are used to create the nanofibers. A range of polymers are used to create nanofibers, depending on their intended application. It includes metals, metal oxides, ceramics, carbon, nonporous and mesoporous materials, hollow structures, core-shell structures, biocomponents, and multi-component materials. It also includes natural and semi-synthetic polymers. For targeted gene delivery, protein and peptide administration, and growth factor delivery, nanofiber composites are a good substitute. Because of their enormous potential for drug delivery, nanofibers can be applied to a wide range of therapeutic fields and have the potential to completely transform them. This review thoroughly examined the types, history, benefits, drawbacks, and polymers employed in nanofiber technology. Additionally, a summary of the types of polymers employed in the creation of nanofibers was provided. The fabrication process, specifically electrospinning and its varieties, is the primary subject of the review study. The study concluded with going over the recent developments and uses of nanofabrication technology.
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